Dave Feldman released preliminary data from a lean mass hyper-responder study that investigates elevated LDL while on a keto diet. He presented the baseline data at the Symposium for Metabolic Health in San Diego, and the reaction was notable — both supportive and critical.
The results of the study have the potential to change how we view elevated LDL cholesterol. But for now, we have to be patient for the end results and cautiously take away the lessons we can from the preliminary data.
Table of content
0:00 Introduction
1:45 Dave Feldman
3:11 The preliminary data from the new LMHR study
10:31 The plaque burden data from the study vs similar cohort
18:51 The current take home from the study
26:07 Could the low LDL findings from the study transcend to cases with higher LDL number?
32:17 The public reaction of the study
36:45 Matthew Budoff, MD
37:38 Any hesitation about the study?
46:57 Dr. Budoff and the ketogenic diet
49:42 Responding to criticism about the length of the study
54:34 Conclusion
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28 responses to “Keto diet and high LDL study – Diet Doctor Podcast”
IS KETO GOOD OR NOT
My view is that if you have a tendency to put on weight then you have to lower your carbs. Carbs are what is driving your hunger. On the plus side, meat and sich are very rich in micronutrients and this means Keto is great for getting everything you need with minimal or inflammation. Going keto makes fasting easy too. I’ve lost 45lbs doing keto and omad together this year. Now my weight is steady and no longer prediabetic. My HDL is up. MY LDL is still high but I think I have to accept that if I want to stay thin and healthy
Having a Hdl/triglycerides ratio of 2 and under is key.
Keto is pretty close to the ideal human diet, carbs as low as possible without being mental about it.
Carbs as low as possible, green veggies are ok, the best ones are the ones you can eat uncooked… less sugar is released in he gut.
animal fat is extremely essential, variety is essential. Don’t loose sleep for not finding that magical grass fed 60$ beef.
Salt for hydration, salt for insulin response.
usually this is enough for most people.
Keto = higher LDL-c which, according to Dave, means to you will probably die tomorrow from heart disease 😂
Yes, keto is good for most people.
My fractionated Lipid results from the Mayo Clinic say I most likely have FH. High LDL 260, low triglycerides 115 (down 60), 40 HDL(up 3). I won’t take statins. Research proves nothing positive about statins. Two of my doctor admit ‘they don’t know how to read the test results’! Jeez. ‘ve been on Keto for 13 months. Lost 80lbs! Feel like a million bucks! Don’t feel like I should worry or do anything. Feeling 99% better than last year.
Same crap here, all was great except that LDL was slightly up. My doctor actually tried to negotiate with me about putting me on a statin, I grew aggravated. But when he said…”How long do you want to live?”…..I walked out.
This will confuse people..We are told that loads of studies have been done and that Keto is good..Sat Fats good, and so on. Getting fed up with so called new studies when we have been told that enough studies have been done to warrent that Keto or low carb is the way to go. This is people’s health here.
How is it confusing? It supports the view that cholesterol guidelines are arbitrary and not a measure of metabolic health or heart disease risk.
Excellent Excellent! Important step in the progress of improving nutritional recommendations.
Are you looking at apo B? Not sure ldl c is relevant.
Wasn’t there a recent study demonstrating the lack of correlation between LDL level and calcium score
Thank you for adding to our knowledge.
Thanks for having us on, Bret. And thanks so much to everyone who has either contributed to the study directly through our charity or is participating directly in the study!
When will you be getting your Nobel Prize, Dave? Can I attend the ceremony?
I have a total serum cholesterol of 7.2 mmol/L What numbers are you using here? And how to convert?
Google is your friend
Great interview’s as well as much needed information. I’ve transitioned from Keto to Carnivore 1 month ago and turbocharged my health it feels
Thank you, Bret! I’ve been ordering my own lab work annually for 4 years now, instead of having a doctor do it. Thanks to YOU and Dave, I ordered lab work last week from Own Your Labs. It was significantly less expensive than the site I used to order through, and that is BEFORE the 10% Citizen Scientist discount. In the interview, Dave mentions that a lot of low carbers don’t have previous blood work to compare to before their dietary intervention. I think I have been getting annual blood work since 2010. I always had low HDL (31-35) and high Trigs (around 200). I thought I was doomed. I was put on blood pressure medication at the age of 38 and met the criteria for Metabolic Syndrome. As an experiment, in 2015, I drank bulletproof coffee every day for three months before getting my annual blood draw. I thought it might be a disaster but just wanted to know. It WASN”T!!! I’ve been keto or low carb ever since with no plans to go back. Last week my HDL was 76, the highest ever. Trigs were 69, the lowest ever. I also did a fasting insulin for the first time with an HbA1c so I could use that “QUICKI” calculator for insulin resistance measuring. Both tests were only 20 bucks! My LDL is 129 (and TC is 217) so of course I devour as much as I can learn about it as a stand alone marker. I like being a guy that weighs 180 instead of 220 (lbs!) for seven years now. People even say I look younger. I’m 59 but people usually assume 45. The LDL and total cholesterol are the only questionable outcomes in my N of 1 experiments. I will stay tuned to this space and thanks again for your work.
Can we listen to the conference? I’m not sure if it was recorded. I’m anxious to hear more about the results of the study as a LMHR myself. Grateful to Dave and his team.
Started low carb in 2019, Total Cholesterol was 217/Triglycerides 96/HDL 40/LDL 158/VLDL 19. Last blood test in 2022 total cholesterol 427/Triglycerides 58/HDL 59/LDL 356/ VLDL 12. Weight in 2019 was around 230, current weight 182. In between that time I’ve been down to 170lbs. I tried to get into Dave Feldman’s study but was rejected LOL. I reckon my LDL scared them off. But I feel a lot better than I used to. My A1C in 2018 was 5.9. Went down in 2020 to 5.6, then back up in 2021 to 5.9 and dropped the same year to 5.8 where it stayed for a year and then this year down to 5.7. Been a weight lifter all my life. Now I have included about an hour of cardio along with the low carb eating daily. I’m pretty sure 6 whole eggs per day sent my cholesterol soaring. I’ve cut down to 2 whole eggs with my breakfast daily. We’ll see what that does to the LDL.
I believe they were looking for people with a higher HDL. I could be mistaken.
LDL is an independent risk marker. The “Diet Doctor” and Dave Feldman are hacks. Doesn’t sound like Feldman’s “study” even has a control. Lmao
Found the vegan…
@gkelley Nope! Lots of animal foods don’t raise LDL. Study the nutritional literature instead of “Diet Doctor” and Dave Feldman.
Finally! I have been waiting for the results ever since the study was announced! Great stuff overall
I admire Dave for his Love of science in medical , it takes courage