💯💯Subscribe for videos on becoming superhuman:
Code SIIM for 10% OFF DoNotAge Longevity Supplements:
Use code SIIM for 20% OFF Alitura Naturals:
Timestamps:
00:35 David Sinclair Supplement Overview
02:05 NMN vs NR
03:46 Resveratrol
04:44 Metformin
05:34 Vitamin D3 and K2
07:23 Baby Aspirin
08:16 Alpha Lipoic Acid
08:53 Spermidine
10:01 Senolytics
10:56 Trimethylglycine TMG
Video Why You Should Take Glycine:
Top 3 Best Longevity Supplements:
Code SIIM for 10% OFF Collagen:
GET MY COFFEE code SIIM10:
OMAD 6 years:
Intermittent Fasting Video Course:
Metabolic Autophagy Master Class:
Metabolic Autophagy 4 Week Meal Plan:
Circadian NAD Activation System:
My Supplement List:
David Sinclair Supplement Stack Review:
MY BOOKS:
Metabolic Autophagy:
Stronger by Stress:
The Immunity Fix:
The Mineral Fix:
The Obesity Fix:
The Collagen Cure:
WIN:
Get Creatine 10% OFF with code SIIM:
Get Vitamin D +10% K2 OFF with code SIIMhttps://donotage.org/product/pure-vitamin-d3-k2-magnesium/
Intermittent Fasting Video Course:
Metabolic Autophagy Master Class:
Metabolic Autophagy 4 Week Meal Plan:
Circadian NAD Activation System:
My Supplement List:
Code SIIM for 10% OFF:
David Sinclair Supplement Stack Review:
NEW Shop:
NEW Merch:
Metabolic Autophagy Book:
Stronger by Stress Book:
The Mineral Fix Book:
The Immunity Fix Book:
Metabolic Autophagy Master Class:
Total Sleep Optimization Video Course:
Metabolic Autophagy 4 Week Meal Plan:
Intermittent Fasting Video Course:
Check Out My Coaching:
Get Self Decode DNA Test with the code SIIM:
Magnesium Breakthrough for a 10% Discount!
Use Code SIIM for 10% Off Self Decode
Use Code SIIM for a 10% Discount on the KAATSU Bands
Get Drink HRW Molecular Hydrogen for 10% OFF With the Code SIIM:
BON CHARGE Blue-Blocking Glasses 15% Discount with the Code SIIM:
Use Code SIIM for a 5% Discount off Do Not Age supplements:
Support the Channel Via PayPal:
Support the channel on Patreon:
💯💯Subscribe for videos on becoming superhuman:
🚻🚻Join my Facebook group:
Disclaimer
I do not own any of the video clips used in this video. The legal rights belong to the legal copyright holders of said content. I have used them under the 'fair use' policy and have done so for entertainment and educational purposes only.
P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.
Follow me on social media:
Blog:
Facebook:
My Facebook Group:
Instagram:
Twitter:
Pinterest:
Patreon:
31 responses to “What You Need to Know About David Sinclair’s Supplements”
Timestamps:
00:35 David Sinclair Supplement Overview
02:05 NMN vs NR
03:46 Resveratrol
04:44 Metformin
05:34 Vitamin D3 and K2
07:23 Baby Aspirin
08:16 Alpha Lipoic Acid
08:53 Spermidine
10:01 Senolytics
10:56 Trimethylglycine TMG
Video Why You Should Take Glycine: https://youtu.be/HhPQOOhsvh0
Top 3 Best Longevity Supplements: https://youtu.be/NspPUvK3KII
Code SIIM for 10% OFF Collagen: https://donotage.org/products/
GET MY COFFEE code SIIM10: https://notyouraverage.coffee/?bg_ref=HGrHgw73NO
OMAD 6 years: https://www.youtube.com/watch?v=QCP2nHXO1Bc
Intermittent Fasting Video Course: https://www.siimland.co/offers/JL2Nx9Rw
Metabolic Autophagy Master Class: https://www.siimland.co/offers/KLk3bLay
Metabolic Autophagy 4 Week Meal Plan: https://www.siimland.co/offers/EwhNysUs
Circadian NAD Activation System: https://www.siimland.co/Circadian-NAD-Activation-System
My Supplement List: https://www.siimland.co/supplement-list
David Sinclair Supplement Stack Review: https://youtu.be/K6cNNktoGl8
The amount of health supplements someone should take should be more than 0 and less than 6, in my opinion.
I’m curious why you say that range. Thanks in advance!
And he is longevity authority … 90% supps he takes are junk 😂
Most of them are fine, he’s just hedging his bets
@Siim Land Well see in 20 years
He’s an mTOR reductionist. Basic logic and reasoning and an understanding of human aging shows this is a myopic view.
Btw Resveratrol still has significant benefits, like activating AMPK.
Even if it doesn’t make you live longer, it probably improves your health span
Time restricted feeding and other basics check the AMPK box. Not sure it warrants a supplement with risk of deuterium.
yeah and it impairs muscle building while yealding the same benefits as cardio. Just do some sport, more effective less expensive
You need really dangerously high doses to reach the necessary concentration for AMPK activation. See [1], it requires 50-100 µM. 50 µM = 11,412µg/l (*). From [2] the maximum concentration in people’s blood after taking 500mg is only 71.181ng/ml = 71.181µg/l. That’s over 160 times less than required!
How about combining it with piperine? See [3], people took 2.5 GRAMS with 25mg piperine. Maximum concentration: 321ng/mL = 321µg/l. Still not enough, you need 4 times of that.
Always check the concentration to see, whether is’t even possible to reach that.
[1] “Resveratrol-Induced AMP-Activated Protein Kinase Activation Is Cell-Type Dependent: Lessons from Basic Research for Clinical Application” (2017)
(*)50 µM = 50 µmol/l = 50*228.25µg/l = 11,412µg/l
[2] “Bioavailability and safety study of resveratrol 500 mg tablets in healthy male and female volunteers” (2016)
[3] “A Randomized, Double-Blind, Dose-Ranging, Pilot Trial of Piperine with Resveratrol on the Effects on Serum Levels of Resveratrol”, 2022
Berberine and glucosamine also activate AMPK pathway
From what I understand from studies listed via the Wellness Messiah with Rimon channel, Resveratrol is more effective on alternate days, and at a lower dose. So I think there may have been updates to how the research has been interpreted since everyone went off taking Resveratrol.
Great video!
Thanks
are there conflicts of interest between sinclair and companies that sell resveratol? Couldn’t find anything after a quick search but I also don’t really know where to search.
You can not compare Sinclair with Johnson. There is always a Bio individuality. Sinclair is not so aligned to exercise and food restrictions. Soon no one takes him so seriously in the longevity realm. IMHO Thanks a lot for your Video, Siim.
Thanks 🙏🏼 I remember he was on joe Rogan and talked about something (I don’t remember) he takes what lowers athletic performance but helps with aging slower. Is there something athletes have to be careful with?
That would be metformin. Makes me feel like sh@t when exercícios.
I used to take gingko biloba but not anymore
What up Siim? Thanks for the detailed info 💪🏾 💯
David Sinclair, current status unknown. I hope there are more high profile people to continue doing spotlight episodes like this.
Resveratrol is a strong estrogen promoter and thus should be avoided as a concentrated supplement.
thankyou for this video
I thought it would be advisable for him to include magnesium in his suppliements.
he does.
When you declare that NMN increase NAD, are you stating that NAD is incresed in the plasma or intracellularly´. If you think that NMN increse NAD in the cell, please give your reference i.e. which study you are referring to and how to access it. Thank you.
The 3 drugs that he takes does not make sense since there are natural alternatives with out such side effects. Be careful before jumping on someone’s bandwagon. By far the best things to aid health & slow ageing is the right diet & exercise plus lower stress. This will also be different for each individual depending on age.
What are his thoughts on methaline blue?
Sonclair is pre-diabetic.
You know what? I used to stop for any mention Sinclair- now I can’t stand him now that I know his stance on NMN ( TRYING TO PROVATISE IT) and how he profited from a flawed resveratrol study- he now, in my mind is exactly….big pharma!
Thanks for listening…