This Protein Mistake Is Nuking Your Kidneys


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56 responses to “This Protein Mistake Is Nuking Your Kidneys”

  1. This is kind of a silly question, but I can’t un-think it now.
    Are kidney beans good or bad for the kidneys?

    • They are incredibly bad for the kidneys, very rich in antinutrients which directly result in kidney stones. They are certainly not a neutral food for kidney health

    • If a person has kidney stones or kidney problems then yes they’re harmful the same way excess phosphorus is going to be harmful for someone with renal failure. For otherwise healthy people they’re not a real issue granted they’re prepared properly

    • @@SiimLand so they are toxic, but you consider them neutral. IMO it would be a lot more health-conscious to just not eat them 🤔

  2. When I read your book “Metabolic Autophagy” a couple years ago, you seemed very pro-animal-based foods, as far as I can remember. Did your opinion change on diet to be more plant-based?

  3. Phosphoric acid is used in Cola instead of citric acid since it is cheaper and provides a better mouth feel than citric acid. The Soda producers are forced to use citric acid in clear drinks like sprite since phosphoric acid is not clear it’s slightly brown. Time to reduce the diet cola and take a magnesium supplement daily I guess.

    • Gesundheit?

      More seriously, this is such an overstated concern. Cooking, soaking, sprouting, fermenting/culturing, etc all significantly reduce phytate content–even more so when you combine two or more different methods.

      For an example: sometimes I make cashew based cheese. First I soak the cashews in boiling water (to kill any mold etc spores on the surface, and soften them up), then I puree them, and then I inoculate the mash with kefir and let it culture for at least a few days before eating.

      Or what about the sprouted oats that I buy, and then I turn around and put boiling water in in a covered pot and let it sit overnight, and then rewarm with some more boiling water + heat in the morning?

      You really think there is much phytates in either of the above by the time they go into my mouth? Nope, very, very little.

      And we come from a long line of animals that evolved to eat a lot of plant food–a lot more plant food than animal foods. You think in those millions of years of evolution, our bodies didn’t adapt to phytates some? Ever notice how much plant foods that chimps and gorillas eat? Seriously? There is new research showing that a certain, moderate amount of phytates may be good and have an antioxidant type role.

      Are you on the carnivore diet?

    • Yes, the fears of Phytates are mostly unfounded despite who you listen to on the internet. The foods that contain them are generally super healthy and you can minimize them if you are worried by all the methods mentioned by the other commenter.

    • Foods containing phytic acid are nutrient-dense, overall. For most people, these foods are important to include in a healthy and well-balanced diet. Some studies have found evidence that phytic acid’s antioxidant effects may prevent conditions such as cancer and osteoporosis.

    • @@stevet5549 see Kim et al. 2020 study “High-phytate/low-calcium diet is a risk factor for crystal nephropathies, renal phosphate wasting, and bone loss”

  4. Damn, i just checked my numbers at Cronometer, and i get 2200mg/day – 3 times too much.
    Don’t know what i should take out of my diet to lower the number.

    100g ground beef
    3-4 eggs
    3 medium/big potatoes

    Those things alone is 1000mg+ of phosphorus.
    When you add fish, vegetables, nuts and seeds you easily end at 2000mg.

    I do get 600mg of magnusium in my diet without supplements too.

    Ppl on carnivore diet must be getting 5000mg+/day.

    • Cal, P, and Vit D are all closely interlinked and has to be balanced. The more P you eat, the more Cal you also need, by extension increases need for vit D as well. Tissue calcification isn’t just about too much calcium alone, as it involves phosphorus, as the two minerals travel together. What matters is where they accumulate to, to your kidney and blood vessels, or to your bone and teeth. D3, Mg, K2, A, these are the four key nutrients required for proper calcium metabolism helping to absorb and to put calcium in the right place (and probably phosphorus too), this help prevent soft tissue calcification and heart disease.

      With phosphorus according to some study, it is the added “inorganic” phosphate that are more concerning, which are added to processed foods. Particularly processed meat. Makes more sense to add more calcium to your diet to balance out the phosphorus. Certain leafy green will have calcium and folate combined, the particular high calcium ones are mustard greens, napa cabbage, and bok choy. Meat and egg have phosphorus and low calcium, they are good for feeding muscle. Dairy have both phosphorus and calcium, they are good for bones.

      Calcium is important for neurotransmitter and muscle control (hence low Mg and Cal, and high P blood level leads to tetany). Dietary calcium is also important for binding oxalate and preventing kidney stones. Supplemental calcium enter the blood stream too quickly, and usually not balanced with the other four nutrients mentioned above so is easier in causing soft tissue calcification. Calcium citrate is the safer supplemental form, it tends to be paired with D3 which is good.

      According to the foods you listed, they are also low folate. Easiest fix would be supplementation. Folate is mainly found in fresh vegetables (as frozen version lacks it). Eating liver every day in order to get enough folate would cause imbalance or toxicity overtime. Although I do know that pasture raised eggs have higher folate amount, but I’m not aware of reliable data for them, and it varies widely with different farming techniques.

    • @@erikahuxley My numbers are:

      Folate: 403ug = 101% of RDA
      Vitamin A: 1515ug = 168% of RDA
      Vitamin D: 830ug = 138% of RDA
      Vitamin K: 440ug = 360% of RDA
      Calcium: 1000mg = 100% of RDA
      Magnesium: 600mg = 150% of RDA
      Phosphorus: 2200mg = 310% of RDA

  5. H3PO4 tastes so good! I wasn’t drinking coke anyway though. I liked the taste but sugar drinks are disgusting

  6. What about those dudes who constantly and consistently eat a lot of protein, and I mean A LOT—way more than is necessary to build muscle, etc? We’re talking way more than 1.2 grams per Kg.

    Pretty sure the kidneys don’t like that so much.

  7. Thanks for another excellent video. Siim, I think it’d be great to dedicate an episode to dedicate an episode to kidney-friendly foods & best practices (e.g. effects of hydration, salt intake, fasting).
    Keep up the great work.

  8. My wife had a kidney transplant, she had/ has genetic kidney disease. In any case, I am well aware of the deal with phosphorus and potassium and kidney function. Once you have kidney disease you need to cut both from the diet to a large degree. With that said, everyone must realize, over your life, kidney function continues to decline even if you have normal kidneys. In my opinion, diet is king, be moderate with all things. People hear something is good for you and in many cases overdo it. Suppliments too, do not think for a minute that they will save you. I don’t think they are completely useless but everyone should strive to get what they need via actual food.

  9. Does this mean the carnivore diet causes kidney disease over time? I eat a lot of dairy but I also eat plant foods that have magnesium but still scared

    • Many people have been carnivores for decades without any health problems. I realize that it only anecdotal, but there is an explanation for why this might be the case. Siim is falling into the problematic mentality of nutritionism. Whole foods are complex profiles of foods that work synergistically. Taurine and many of the fat-soluble vitamins regulate numerous systems, including controlling how the body uses other nutrients, such as maintaining the appropriate balance of minerals. Taurine will help the body eliminate excesses or, when insufficient, hold onto them.

    • I can state my n=1 tests, my eGFR increased 30 points on a carnivore diet, but that does not translate to overall healthy vascular system, as per this presentation. Based on the filtration improvement, I doubt that the carnivore diet cause kidney disease, as usual, over indulgence will.

    • @@MarmaladeINFP but is that a yes or a no that carnivore or high animal protein in general can lead to kidney disease one day?

  10. I believe in the future it will be discovered that eating high carbs and proteins together in the same meal accelerates the production of AGEs. As both are being digested at the same time you have an unnatural situation where you simultaneously have high glucose and free protein in the blood at the same so higher chance of these two reacting together to produce AGEs. If you think about it this situation is unnatural and wouldn’t occur in nature. You would be either eating one or the other but not both at the same time

    • Carbs and fats in the same meal is also unnatural. Fats promote a temporary insulin resistance effect upon consumption, which in theory is going to cause a blood sugar raise that is longer in duration, and any rise in blood sugar seems to promote inflammation. The standard american diet defaults to carbs/fats because combined they are so addictive and promote a larger dopamine spike.

  11. So if 3 days a month my phosphorus ratio is higher but lower on everyother day then a safe bet? I also read that boiling animal products massively reduces phosphorus

  12. Probably one of your best videos so far. CKD or kidney disease is a so called ‘silent disease’ which a lot of people are suffering from without knowing it. And as you say, there is no one diet. When will you create a video showing optimal blood work ranges, and what to aim?

  13. Many people have been carnivores for decades without any health problems. I realize that it only anecdotal, but there is an explanation for why this might be the case.

    Part of the problem with this video is that Siim is falling into the problematic mentality of nutritionism. Whole foods are complex profiles of foods that work synergistically.

    Taurine and many of the fat-soluble vitamins regulate numerous systems, including controlling how the body uses other nutrients, such as maintaining the appropriate balance of minerals. Taurine will help the body eliminate excesses or, when insufficient, hold onto them.

    • I don’t have to rely on nutritionism or mechanisms when we’ve got heaps of clinical trials and cohort studies

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