Longevity Scientist Breaks Down What Causes Aging of Cells – Matt Kaeberlein PhD


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Timestamps:
01:00 Senescent Cells and Aging
09:18 Bon Charge Sponsorship
10:00 Immune System Aging
15:08 What Triggers Cell Senescence
18:50 How to Measure Cell Senescence
22:58 Senolytic Supplements and Drugs
35:50 mTOR, Rapamycin and Senescence
38:25 Aging and Autoimmunity
46:00 Recent Study on IL-11 and Life Extension
55:00 Mice Living Pathogen Free in Labs

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22 responses to “Longevity Scientist Breaks Down What Causes Aging of Cells – Matt Kaeberlein PhD”

  1. Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland
    Timestamps:
    01:00 Senescent Cells and Aging
    09:18 Bon Charge Sponsorship
    10:00 Immune System Aging
    15:08 What Triggers Cell Senescence
    18:50 How to Measure Cell Senescence
    22:58 Senolytic Supplements and Drugs
    35:50 mTOR, Rapamycin and Senescence
    38:25 Aging and Autoimmunity
    46:00 Recent Study on IL-11 and Life Extension
    55:00 Mice Living Pathogen Free in Labs

    Matt Kaeberlein Optispan YouTube Channel: https://www.youtube.com/@optispan

    Get my new book The Longevity Leap: https://www.siimland.co/thelongevityleap

  2. I looked up IL-11 and found that fish oil might help resolve it(?). I had read Dr Sears book, “The Resolution Zone” about resolving inflammation being the key, and that proper diet, and fish oil specifically, resolves inflammation.

  3. Thanks, two favourites together. Where to go to blood test i Riga? Siim Land mentioned in a previous video that blood testing was inexpensive (based on the price he mentioned) in his country. So is probably Riga also, and it is easy to fly there.

  4. I’m wondering; since exogenous testosterone lowers LH, does artificially lowering testosterone in turn increase LH?

    • Or live so long that humanity evolves enough that people can maintain physical bodies while obtaining spiritual enlightenment sufficient to astral travel into higher-dimensional worlds, finally bringing heaven and earth back together… that’s my goal, at least…

    • @@harrisonschwartz565 Hebrews 9:27:
      And as it is appointed unto men once to die, but after this the judgment:

  5. moderate-vigorous physical activity can slow the premature senescence of immune cells in sedentary adults with obesity

  6. Niacin – the flushing kind will increase cellular detoxification especially if combined with sauna, whirlpool, or exercise
    Niacin is also a precursor for NAD
    Some recommend the non flushing kind for NAD

  7. Upon waking — a glass of water with about 2 teaspoons of salt in water— will sometimes cause – diarrhea – which is a form of mini-detoxificaton

  8. Quercetin , Fisetin , Curcumin , EGCG , Piperlongumine , intermittent fasting has shown promise in clearing senescent cells

  9. So to sum up, you’re saying that we don’t have enough information to even talk about this so why are you talking about it?

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