I’m 40 But My Biological Age is 23. Here’s How I Did It – Chris Mirabile


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Timestamps:
00:22 How Chris Started Slowing His Biological Age
05:00 What Are the Hallmarks of Aging
14:15 Targeting All Hallmarks of Aging At Once
18:15 Clinical Trials on Novos Core
27:30 Rejuvenation Olympics
36:30 Longevity Tests and Biological Age Clocks
46:29 Chris' Longevity Routine
59:35 Is Chris Getting Healthier in His 40s or Not

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26 responses to “I’m 40 But My Biological Age is 23. Here’s How I Did It – Chris Mirabile”

  1. Timestamps:
    00:22 How Chris Started Slowing His Biological Age
    05:00 What Are the Hallmarks of Aging
    14:15 Targeting All Hallmarks of Aging At Once
    18:15 Clinical Trials on Novos Core
    27:30 Rejuvenation Olympics
    36:30 Longevity Tests and Biological Age Clocks
    46:29 Chris’ Longevity Routine
    59:35 Is Chris Getting Healthier in His 40s or Not

    Longevity and Anti-Aging Playlist: https://www.youtube.com/watch?v=5KNsfEBXKMg&list=PLMaXsmhvb0r2zcztetf3oE6_zKOm9TebR&ab_channel=SiimLand

  2. Please also make a video on how to increase mean sexual health and night time erections

  3. Gonna try that face scan and look more into this product. what was the step count that was “too much”?

  4. Skin care. Nothing. No soap or shampoo and wholesome high Protein diet. I dwim daily and use sauna/steambath. Wonder what is hostory of daily shampooing of hair, bodywash and skincare unctions? At almost 70yrs am oldest OG under the barbell at local YMCA. Appear to be thriving. 🏋🏻🏋‍♂️🦊

  5. Where is the actionable information? Most of this is well known by people following Siim. Here’s some advice – keep videos under 10 minutes, give out actionable information. The detail of the protocols can be obtained from longer format videos for those who are into the research end of this.

  6. Someone previously asked about step count in a now deleted comment, and at what point does increased step count start to negatively affect epigenetic age. . I am going to guess the study below was the relevant study referred to by the guest. It looks like grimage increased after around 11,2471 daily steps . There are u shaped curves based upon amount of vigorous exercise and MET hours as well. Though the study appears to differ from what the guest said. The way I read the graphs, is that those that did the most exercise had the same or worse grimage results than those that did the least, as the curves were relatively constant on both ends. This would suggest to me that overdoing it by a large amount may wipe out all of the benefit that exercise has in terms of grimage results. That is, if you believe that grimage optimization has benefits.

    Fox FAU, Liu D, Breteler MMB, Aziz NA. Physical activity is associated with slower epigenetic ageing-Findings from the Rhineland study. Aging Cell. 2023

    • Of course, grimage seems to be a dopey mesaurement when we have mortality stats. For those under 60, we see decreasing all cause mortality with step counts going up to at least 16,000 steps daily in vthis meta analysis Mortality may decrease further for those under 60 after 16000 steps, but the graph in the study stopped at 16000. For those 60 or over, mortality increased after 8000 steps, suggesting that seniors should not overdo it.

      Paluch AE, Bajpai S, Bassett DR, Carnethon MR, Ekelund U, Evenson KR, Galuska DA, Jefferis BJ, Kraus WE, Lee IM, Matthews CE, Omura JD, Patel AV, Pieper CF, Rees-Punia E, Dallmeier D, Klenk J, Whincup PH, Dooley EE, Pettee Gabriel K, Palta P, Pompeii LA, Chernofsky A, Larson MG, Vasan RS, Spartano N, Ballin M, Nordström P, Nordström A, Anderssen SA, Hansen BH, Cochrane JA, Dwyer T, Wang J, Ferrucci L, Liu F, Schrack J, Urbanek J, Saint-Maurice PF, Yamamoto N, Yoshitake Y, Newton RL Jr, Yang S, Shiroma EJ, Fulton JE; Steps for Health Collaborative. Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. Lancet Public Health. 2022

  7. Siim i love ur vids man, can u pls do a video on lik the top 10 or 15 supplements to take for longevity? I follow a lot from u and from blueprint and try to combine it to make my own routines!

  8. Siim, which epigenetic test(s) do you recommend?

    Want to do a before / after intervention 🔍

    Great episode! 👏

    • If you can make a YouTube account and comment at 83 years old you’re not doing to bad haha God bless, definitely keep watching these videos and being here

  9. I figured out I can consume fish skin in the blender and I’ll try raw liver with fruit juice. Is this. A longevity protocol?

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