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Timestamps:
00:00 Introduction
00:37 Twenty since Aubrey coined the Longevity Escape Velocity
11:13 When will we reach Longevity Escape Velocity
16:45 Slowing down aging vs regeneration
19:44 What breakthroughs we need for longevity escape velocity
24:00 Seven types of aging damage that needs to be repaired
24:37 Loss of cells and stem cells
33:57 Regenerating limbs and organs
36:10 Mitochondrial free radical theory of aging
41:15 Intracellular and Extracellular waste products
47:15 How far is gene therapy now?
49:15 Death resistant cells
53:52 Do you need long telomeres
57:15 Extracellular matrix stiffening and glycation
01:00:48 Biggest breakthroughs in the next 5 years
01:04:30 What to do to live until the longevity escape velocity
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33 responses to “Leading Longevity Scientist Predicts Dramatic Life Extension by 2035 – Aubrey de Grey”
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Timestamps:
00:00 Introduction
00:37 Twenty since Aubrey coined the Longevity Escape Velocity
11:13 When will we reach Longevity Escape Velocity
16:45 Slowing down aging vs regeneration
19:44 What breakthroughs we need for longevity escape velocity
24:00 Seven types of aging damage that needs to be repaired
24:37 Loss of cells and stem cells
33:57 Regenerating limbs and organs
36:10 Mitochondrial free radical theory of aging
41:15 Intracellular and Extracellular waste products
47:15 How far is gene therapy now?
49:15 Death resistant cells
53:52 Do you need long telomeres
57:15 Extracellular matrix stiffening and glycation
01:00:48 Biggest breakthroughs in the next 5 years
01:04:30 What to do to live until the longevity escape velocity
I yet to hear from this guys a single practical advice on how to reverse aging. None. He always come up with nonsense terms
Because the current practical advice isn’t going to take us beyond 120 years of age. But yes, he’s more of a visionary
@@SiimLand very true
he’s a scientist, not a physician. his field are the things that not yet work. it’s bonkers to ask him for practical advice.
At the very end he advises diet , exercise and staying away from dangerous countries 😂
@ClaudeDiamond after like 30 years of research, he comes up with this haha
Caloric restriction is not fasting. And fasting mimicking supplements and diets is not fasting. Nothing can mimick fasting. You need to target lots of pathways at once
BUT they are money making things to keep business going. Imagine if the whole western world realised they could be so more healthy by not eating. And when you do eat you eat only fresh produce… They will never let that happen with there drugged up food that has withdrawl symptoms.
“Need”.
Peptides❤ ! Don’t die ❤Decentralization ❤
Transhumanist nonsense, this channel has officially Jumped the Shark.
This channel has always been about longevity.
Not wanting to rot away and die in pain due to the grinding wheel of time is about as transhumanist as not wanting to die of sepsis because you cut your toe on a random rock in the forest.
Yeah, it was all good for you, all the hundreds of videos, but now it’s bad after one video…
@@marcell199311haha right
Oh cause you’re not already a transhumanist ?
Technology has made your life unimaginably better and you’re currently using it. Are you insane ?
I posted a reply yet YouTube took it down. You can’t bag big business using food with withdrawal symptoms to keep you not willing to fast… Maybe using different words with the same meaning works?
The decision not to fast rests with the individual. The food industry is not responsible for an individual’s and irresponsibility and weakness.
I intentionally subject myself to ranges of moderate to severe caffeine withdrawal accompanied by 16-24 hour fasts 2 to 3 times a week.
Having to go through withdrawal is not an excuse for being a 🐱.
Stoked for this episode 🙌🏽
Aubrey’s take on methylene blue?
That would be interesting to know.
While a lot of this is speculation, I’m not sure many people appreciate how likely a lot of this is to become a reality. It’s just a question of time and money. If all of the West were to devote its efforts and resources to this end, LEV would pretty much become a certainty in the next decade or so. That’s why, speculation though it may be, it’s incredibly important to make more people aware of this research and secure more funding.
Facts
Awesome. Thanks Siim!
Sounds good to me
I like you Siim but Aubrey is a fraud
Whew, arguments ?
And if you go about how he’s done it for 25 years without results well.. it’s not an easy job nor a one man job, he is pushing things in the right direction which is already amazing
“Right to try” should be introduced everywhere in the world.
Because mice trials just dont cut it.
On the other hand, I’m pretty sure solving brain-computer interfaces and immune-rejection will probably be a lot easier than solving all the problems the body accumulates with age and I dont see the problem with replacing an organ with a machine to live longer… except the brain of course.
My secret to longevity is “not to die every single day!”
This was more like a philosophy class, than factual science. I enjoyed it, but it’s not for everyone.
How can he make a guess on 2035 when we don’t have a single working age reversal treatment? At least when the tech companies make grandiose claims about the singularity they have progress to show in artificial intelligence.
We’ll know age reversal has happened when Aubrey de Grey looks like he’s 21. 😄